Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino-acid neuropeptide that acts as a hormone and neurotransmitter in the body. It regulates immunity, blood flow, and digestion, and is frequently used in peptide therapy to help manage Chronic Inflammatory Response Syndrome (CIRS) and respiratory issues. [1, 2, 3]

Key Functions

• Immune Regulation: It serves as a potent anti-inflammatory agent, decreasing pro-inflammatory cytokines and protecting against various autoimmune conditions.

• Digestion: It triggers the secretion of water and electrolytes in the gut while relaxing smooth muscles, promoting digestion.

• Cardiovascular & Pulmonary: VIP functions as a vasodilator, opening blood vessels and dilating airways to improve respiratory function. [1, 2, 3, 4, 5]

Clinical & Therapeutic Uses

• CIRS & Mold Illness: VIP is often utilized in nasal spray form as the final step in the Shoemaker Protocol to help restore normal brain function and balance the immune system for patients recovering from mold toxicity.

• Respiratory Therapeutics: Because of its bronchodilatory properties, inhaled VIP has been studied for conditions involving inflammation and pulmonary hypertension.

• Wellness & Energy: Some wellness clinics utilize VIP therapy to support overall homeostasis, which users report can feel stabilizing and energizing